TESA / PESA / MESA / TESE / Micro TESE

PESA (Percutaneous Epididymal Sperm Aspiration) and TESA (Testicular Sperm Aspiration) are methods used for surgical sperm aspiration. PESA is a method wherein sperm is collected from epididymis using a syringe and fine needle. TESA is a method wherein sperm is retrieved directly from the testicles. This is commonly used for men with azoospermia due to primary testicular disease (Very low sperm production in testis). In these men usually, there will be no sperm in the epididymis and testicular sperm retrieval is needed.

If these procedures fail to retrieve sperm, then testicular sperm extraction (TESE) or micro TESE, which are open testicular biopsies, are performed to retrieve sperm.

Indications
  • Azoospermia due to primary testicular disease
  • Obstruction to the genital tract due to infection or previous surgery
  • Congenital absence of the vas deferens, commonly seen in the patients with cystic fibrosis
  • Patients with vasectomy
Microscopic illustration showing multiple sperm cells surrounding and penetrating a human egg cell during the process of fertilization

Step 1

These surgical procedures can be performed under local anesthetic or sedation, depending on the preference of the patient and the clinician. The patient can go back to work within 4-5 days and usually advised to wear a scrotal support for 48 hours in order to protect the scrotum and testes. The patient may experience mild discomfort following the procedure.

Step 2

As the sperm retrieved with these procedures is limited, ICSI (Intra Cytoplasmic Sperm Injection) is the preferred method of fertilization of egg. If we get more sperm, then the extra sperm are cryopreserved or frozen for future use, such that we do not have to subject the man to further surgical procedure.

Southern Gem Hospital

Frequently Asked Questions

Find answers about TESA, PESA, TESE, Micro TESE and advanced surgical sperm retrieval treatments at Southern Gem Hospital in Hyderabad.

What is PESA and TESA?

PESA (Percutaneous Epididymal Sperm Aspiration) is a method wherein sperm is collected from the epididymis using a syringe and fine needle. TESA (Testicular Sperm Aspiration) is a method wherein sperm is retrieved directly from the testicles. Both are surgical sperm retrieval procedures used for men with azoospermia and male factor infertility.

What is the difference between TESA, PESA, TESE and Micro TESE?

PESA collects sperm from the epididymis using a fine needle. TESA retrieves sperm directly from the testicles using aspiration. If PESA and TESA fail to retrieve sperm, then TESE (Testicular Sperm Extraction) or Micro TESE, which are open testicular biopsies, are performed to retrieve sperm. MESA (Microsurgical Epididymal Sperm Aspiration) is a microsurgical form of epididymal sperm retrieval.

Who needs TESA or PESA treatment?

TESA and PESA are indicated for men with azoospermia due to primary testicular disease, obstruction to the genital tract due to infection or previous surgery, congenital absence of the vas deferens (commonly seen in patients with cystic fibrosis), and patients who have had a vasectomy.

Is TESA or PESA a painful procedure?

TESA and PESA are performed under local anaesthetic or sedation, depending on the preference of the patient and the clinician. The patient can usually go back to work within 4-5 days and is advised to wear a scrotal support for 48 hours to protect the scrotum and testes. The patient may experience mild discomfort following the procedure.

What happens to the sperm retrieved through TESA or PESA?

As the sperm retrieved through TESA or PESA is limited, ICSI (Intra Cytoplasmic Sperm Injection) is the preferred method of fertilisation of the egg. If more sperm are retrieved, the extra sperm are cryopreserved or frozen for future use, so that the man does not have to undergo further surgical procedures.

Can men with azoospermia have children using TESA or PESA?

Yes. Men with azoospermia due to primary testicular disease can have genetically related children using TESA or PESA combined with ICSI. Even when TESA and PESA fail, TESE or Micro TESE (open testicular biopsies) can be performed to retrieve sperm. The retrieved sperm is then used for ICSI fertilisation.

Is TESA, PESA, TESE treatment available at Southern Gem Hospital Hyderabad?

Yes. Southern Gem Hospital, Hyderabad offers TESA, PESA, MESA, TESE and Micro TESE surgical sperm retrieval procedures at both its Basheerbagh and Banjara Hills branches. For appointments, call +91 40 6658 5555 or +91 80964 14440.

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